What is your life story?
What do you dream of achieving?
What is your personal plan of action to get where you want to go?
 
Go into every interview planning to answer these questions. You'll be surprised at how much more genuinely you can connect with the person on the other end of the conversation. If your answers to these questions don't line up with how the company/team approaches their own culture, then no matter how awesome the companies' product is then its likely in your best interest to walk away.

Remember, interviewing is not about subjecting yourself to an interrogation. It's about evaluating if the relationship is mutually beneficial for everyone involved.